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Antibodiesinc/Pan-Neurofascin (extracellular)/75-172/1 Ea
Antibodiesinc/Pan-Neurofascin (extracellular)/75-172/1 Ea
商品编号：
75-172
市场价：
¥0.00
美元价：
0.00
产品分类：
重组抗体
公司分类：
Recombinant_antibodies
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Lipid raft fractions isolated from adult rat brain. Target identified as Neurofascin by:
- binding to NF-186-tranfected COS cells
- recognition of NF155 and NF186 but not other highly related L1 CAMs like NrCAM
- immunoprecipitation of NF155 and NF186 and confirmation by mass spectrometry
- loss of immunostaining against NF186-shRNA knockdown samples
Rat: amino acids 25-1110 (extracellular domain common to NF155 and NF186)
Mouse: 98% identity (1074/1086 amino acids identical)
Human: 79% identity (955/1195 amino acids identical)
This NeuroMab antibody is considered "Restricted" and is therefore not available for commercial re-distribution on a for-profit basis.
- binding to NF-186-tranfected COS cells
- recognition of NF155 and NF186 but not other highly related L1 CAMs like NrCAM
- immunoprecipitation of NF155 and NF186 and confirmation by mass spectrometry
- loss of immunostaining against NF186-shRNA knockdown samples
Rat: amino acids 25-1110 (extracellular domain common to NF155 and NF186)
Mouse: 98% identity (1074/1086 amino acids identical)
Human: 79% identity (955/1195 amino acids identical)
This NeuroMab antibody is considered "Restricted" and is therefore not available for commercial re-distribution on a for-profit basis.
Specifications:
Target |
|
Pan-Neurofascin (extracellular) |
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Applications |
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Immunoblot (IB) Immunohistochemistry (IHC) Immunoprecipitation (IP) |
|
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Clone |
|
A12/18 |
|
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IgG Isotype |
|
IgG2a |
|
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Species Reactivity |
|
Rat (R) |
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Validation |
|
Br-IB Br-IHC T |
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Type |
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Purified |
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Format |
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100 ul |
|
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Cross Reactivity |
|
None Reported |
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Expected Banding Pattern |
|
155, 186 kDa |
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Host |
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Mouse (M) |
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Label |
|
Unlabeled |
|
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Antibody Type |
|
Monoclonal |
|
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Commercial Price |
|
450 |
|
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Non-Profit Price |
|
200 |
|
|
||
Distributor Price |
|
Per Contract(QUOTE) |
|
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ABID |
|
RRID:AB_2282826 |
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品牌介绍
当抗体公司（Antibodies Incorporated）在1962年开业时，与抗体相关的研究才刚刚开始。创始人Jim Hillman拥有博士学位。从药理学明尼苏达大学，来到加州大学戴维斯分校在免疫化学完整的博士后工作，在工作期间，他学习了加州理工学院（加州理工学院）根据丹·坎贝尔，领域的先驱。吉姆带来了他的妻子，公司的共同创始人卡罗尔（Carol）和两个孩子，以及使用基于抗体的化学疗法寻找治疗癌症的能量和想法。具体地说，吉姆认为，如果他能够识别并分离出可能具有抗原性的肿瘤部位（一个焦点是淋巴肉瘤），则可能有可能进行有效的基于抗体的治疗。吉姆寻找这种治疗方法的梦想推动了他的工作多年。
